Gut virome-colonising Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivo

Conclusion
This study described HBx as a contributor to the UC pathogenesis and provides a new perspective on the virome as a target for tailored treatments.

Source: Gut - September 13, 2023 Category: Gastroenterology Authors: Massimino, L., Palmieri, O., Facoetti, A., Fuggetta, D., Spano, S., Lamparelli, L. A., D'Alessio, S., Cagliani, S., Furfaro, F., D'Amico, F., Zilli, A., Fiorino, G., Parigi, T. L., Noviello, D., Latiano, A., Bossa, F., Latiano, T., Pirola, A., Mologni, L. Tags: Open access, Gut Inflammatory bowel disease Source Type: research