Dynamic plasmid copy number control for synthetic biology

Trends Biotechnol. 2023 Sep 7:S0167-7799(23)00238-X. doi: 10.1016/j.tibtech.2023.08.004. Online ahead of print.ABSTRACTPlasmids that replicate independently from chromosomes are valuable genetic tools for biological research. Dynamic control of plasmid copy number facilitates flexible regulation of the gene of interest or the genetic circuit installed in the plasmid. This useful strategy is being integrated into synthetic biology for metabolic reprogramming and biosensing applications.PMID:37689527 | DOI:10.1016/j.tibtech.2023.08.004
Source: Trends in Biotechnology - Category: Biotechnology Authors: Source Type: research