Novel ALK immunohistochemistry assay (clone OTI1A4, Dako) is a sensitive, reliable marker for identifying ALK rearrangements in lung adenocarcinomas : A validation study

CONCLUSIONS: Immunohistochemistry-based assays provide a valid and reasonably priced alternative, especially in settings where molecular confirmatory tests are neither offered nor accessible. Given high interassay and molecular concordance, we propose that the novel Dako OTI1A4 assay can be reliably used to identify cases with ALK rearrangement.PMID:37681660 | DOI:10.1093/ajcp/aqad111

Source: American Journal of Clinical Pathology - September 8, 2023 Category: Pathology Authors: Ozgur Can Eren Cisel Aydin Mericoz Emine Bozkurtlar Pinar Bulutay Arzu Baygul Ibrahim Kulac Source Type: research