Estrogen deprivation effects of endocrine therapy in breast cancer patients: incidence, management and outcome

With more than 2 million new diagnoses per year, breast cancer (BC) is the most common malignancy and the leading cause of cancer-related death worldwide [1]. Most BC cases are diagnosed at an early stage, with the disease limited to the mammary gland and the loco-regional lymph nodes. Hormone receptor positive (HR-positive) BC is the most frequent molecular subtype, accounting for about 70% of the diagnoses [2].Fig 1.Table 1.

Source: Cancer Treatment Reviews - September 7, 2023 Category: Cancer & Oncology Authors: Linda Cucciniello, Giovanna Garufi, Rossana Di Rienzo, Claudia Martinelli, Giuliana Pavone, Mario Giuliano, Grazia Arpino, Filippo Montemurro, Lucia Del Mastro, Michelino De Laurentiis, Fabio Puglisi Tags: Anti-tumour Treatment Source Type: research