Single-Time-Point Imaging for Dosimetry After [177Lu]Lu-DOTATATE: Accuracy of Existing Methods and Novel Data-Driven Models for Reducing Sensitivity to Time-Point Selection

Conclusion: The performance of the Madsen method and proposed data-driven models is less sensitive to TP selection than is the Hänscheid method. At the earliest TP, which is the most practical, the model incorporating baseline biomarkers outperforms other methods that rely only on the single activity measurement.

Source: Journal of Nuclear Medicine - September 1, 2023 Category: Nuclear Medicine Authors: Wang, C., Peterson, A. B., Wong, K. K., Roseland, M. E., Schipper, M. J., Dewaraja, Y. K. Tags: Clinical Investigations Source Type: research