The genetic aspects of hidradenitis suppurativa

The genetic aspects have a substantial role in HS pathogenesis. A positive family history of HS occurs in about one-third of HS cases and is significantly higher in patients with early onset of the disease. Recent twin studies have shown a high heritability in HS, fortifying the importance of genetic factors in disease pathogenesis. Based on existing knowledge on the genomics of HS, the disease can be categorized as familial, sporadic, syndromic HS, and "HS plus" associated with other syndromes.
Source: Clinics in Dermatology - Category: Dermatology Authors: Source Type: research