Effect of Dexamethasone on Modulating Lp(a) Levels in COVID-19 Pneumonia

It has been hypothesized that patients with COVID-19 and elevated Lipoprotein(a) have increased Interleukin-6 (IL-6) and an exaggerated inflammatory response. Moriarty, et al, hypothesized that elevated Lp(a) during COVID-19 could be a predictor of the severity of infection. Nurmohamed, et al. observed that Lp(a) increased by 16.9 mg/dL over 3 weeks in patients with COVID-19 and is strongly correlated with an increase in IL-6. They also observed a trend between the delta of IL-6 and ICU admission.
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Tags: Clinical Application of Biomarkers Source Type: research