† Pharmacokinetics of Mibavademab in Healthy Participants: Results from a Randomized, Phase 1, Two-Part, First-in-Human Study

Leptin is a circulating adipose-derived hormone that controls energy expenditure and glucose/lipid metabolism by binding to leptin receptors (LEPRs); leptin is critical for body weight homeostasis and is a target for replacement therapy in treating obesity due to leptin deficiency.

Source: Journal of Clinical Lipidology - July 1, 2023 Category: Lipidology Authors: Jeanne Mendell, Andrew Gewitz, Yuhuan Wang, Lutz Harnisch, Benjamin A Olenchock, Hao Pan, Simona Podgrabinska, Wenjun Zheng, An Zhao, Fr édéric Vanhoutte, John D Davis Tags: Novel Therapies in Lipid Management and Co-Morbidities Source Type: research