Selective Blockade of Interleukin-6 Trans-signaling

Atrial fibrillation (AF) has been accepted as an inflammatory atrial myopathy. Interleukin 6 (IL-6)-dependent inflammatory signaling pathways take context-dependent effects on cardiovascular diseases. The IL-6 trans-signaling is predominantly pro-inflammatory. However, its effect on AF is unclear.

Source: Heart Rhythm - August 24, 2023 Category: Cardiology Authors: Xintao Li, Xiaoyu Wu, Xiaoqiang Chen, Shi Peng, Songwen Chen, Genqing Zhou, Yong Wei, Xiaofeng Lu, Changzuan Zhou, Yutong Ye, Jun Li, Shaowen Liu, Juan Xu Source Type: research