GSDMD knockdown attenuates phagocytic activity of microglia and exacerbates seizure susceptibility in TLE mice

Temporal lobe epilepsy (TLE) is often characterized pathologically by severe neuronal loss in the hippocampus. Phagocytic activity of microglia is essential for clearing apoptotic neuronal debris, allowing for...

Source: Journal of Neuroinflammation - August 23, 2023 Category: Neurology Authors: Xiaoxia Yang, Qingqing Cao, Yi Guo, Jingchuan He, Demei Xu and Aolei Lin Tags: Research Source Type: research