Age effects on motor threshold

Background: rTMS is a clinically effective antidepressant treatment in elderly patients1. The brain's cortical excitability depends on cortical thickness and the distance between the coil and the cortex. Both cortical thickness and the coil-cortex distance could be affected in elderly due to the cortical atrophy occurring with age2. However, previous studies3 –8 were inconsistent.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 1, 2023 Category: Neurology Authors: Christiane Licht, Alexandra Alario, Benjamin Pace, Anthony Purgianto, Mark Niciu, Thomas Nickl-Jockschat, Nicholas Trapp, Aaron Boes Source Type: research