4-hydroxylonchocarpin and corylifol A: The potential hepatotoxic components of Psoralea corylifolia L

This study suggests that 4-hydroxylonchocarpin and corylifol A cause hepatocyte injury and apoptosis by inducing oxidative stress and mitochondrial dysfunction, suggesting that these compounds may be the potential hepatotoxic components of P. corylifolia.PMID:37598872 | DOI:10.1016/j.toxlet.2023.08.008

Source: Toxicology Letters - August 20, 2023 Category: Toxicology Authors: Linqi Ouyang Zhiqiang Fan Yang He Long Tan Guoyan Deng Qin He Yiran He Ting Ouyang Congjie Li Qin Zhang Hongyu Liu Yajie Zuo Source Type: research