Development of peptide-based ratiometric fluorescent probe for sensing heparan sulfate and heparin in aqueous solutions at physiological pH and quantitative detection of heparan sulfate in live cells

This study presents the first ratiometric fluorescent probe capable of quantitatively detecting HS levels in aqueous solutions and live cells. The unique properties of peptide-based probe 3 make it a valuable tool for studying HS biology and potentially for diagnostic applications in various biological systems.PMID:37595478 | DOI:10.1016/j.bios.2023.115595

Source: Biosensors and Bioelectronics - August 18, 2023 Category: Biotechnology Authors: Sumita Subedi Hyun Jung Hwang Donghee Kang Pramod Kumar Mehta Nayeon Kim Hyojin Park Jae-Seon Lee Keun-Hyeung Lee Source Type: research