To eat or not to eat: type 2 immunity controls food avoidance behavior

Trends Immunol. 2023 Aug 15:S1471-4906(23)00154-0. doi: 10.1016/j.it.2023.07.007. Online ahead of print.ABSTRACTGrowing evidence suggests that food allergies are regulated by neuroimmune interactions. However, the underlying molecular mechanisms remain unclear. Plum et al. and Florsheim et al. identify IgE-mediated mast cell activation, leukotrienes, and growth differentiating factor 15 (GDF15) as key regulators of the avoidance response to food allergens in mice.PMID:37586904 | DOI:10.1016/j.it.2023.07.007
Source: Trends in Immunology - Category: Allergy & Immunology Authors: Source Type: research