Bilateral Primary Orbital Xanthogranulomas: A Case Report and Comparison of Xanthomatous Conditions

Xanthoma is a benign lesion of foamy macrophages or histiocytes, also called xanthoma cells. Xanthogranuloma is a related but distinct lesion characterized by the presence of Touton giant cells in addition to xanthoma cells. Xanthomas are most often found in patients with primary or secondary dyslipidemia, including familial dyslipidemias, and can be important markers of such conditions.1,2 Xanthelasma (often found on the eyelids), plane xanthoma, verruciform xanthoma and tendon xanthoma are histopathologically similar entities that present as soft, yellow plaques containing cholesterol found in the dermis, mucous membranes, or tendons.
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Tags: Case Study Source Type: research