Inhibition of PI3K p110 δ activity reduces IgE production in IL-4 and anti-CD40 stimulated human B cell cultures
In conclusion, PI3K p110δ signalling is required for the production of human IgE, which makes it a pharmacological target for the treatment of allergic disease.PMID:37530226 | DOI:10.1111/imm.13684
Source: Immunology - Category: Allergy & Immunology Authors: Anna Cutrina-Pons Aloka De Sa David J Fear Hannah J Gould Faruk Ramadani Source Type: research
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