Survivin degradation by bergenin overcomes pemetrexed resistance

ConclusionsSurvivin overexpression is required for maintaining multiple malignant phenotypes of NSCLC cells. Bergenin exerts a potent antitumor effect on NSCLC via targeting survivin, rendering it a promising agent for the treatment of NSCLC.

http://link.springer.com/10.1007/s13402-023-00850-5

Source: Cellular Oncology - August 5, 2023 Category: Cancer & Oncology Source Type: research