S100A9 Regulated M1/M2 Macrophage Polarization in Interleukin-10-Induced Promotion of Malignant Pleural Effusion

In conclusion, S100A9 plays a vital role in the process of IL-10 deficiency-mediated MPE suppression by regulating M1/M2 polarization, thus influencing the tumor-migration capacity and apoptosis. This could result in clinically applicable strategies to inhibit the formation of MPE by regulating the polarization of MPE macrophages.PMID:37533789 | PMC:PMC10393522 | DOI:10.1155/2023/3473464
Source: Journal of Immunology Research - Category: Allergy & Immunology Authors: Source Type: research