< em > Naoluo Xintong < /em > Decoction activates caspase-1/Gasdermin D pathway to promote angiogenesis of rat brain microvascular endothelial cells after oxygen glucose deprivation/reperfusion injury

CONCLUSION: NLXTD can improve the proliferation, migration, and tube- forming ability and promote angiogenesis of BMECs with OGD/R injury probably by inhibiting the caspase-1/Gasdermin D pathway in pyroptosis, alleviating cell injury, and upregulating the expressions of VEGF and VEGFR2.PMID:37488791 | PMC:PMC10366515 | DOI:10.12122/j.issn.1673-4254.2023.07.05

Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: P Li Y Hu J Liu L Wang Y Wu J Hu Source Type: research