Changes in the extracellular matrix at microvascular obstruction area after reperfused myocardial infarction: A morphometric study

CONCLUSIONS: ECM composition in infarcted regions with MVO isolated from female swine displays a higher presence of inflammatory infiltrate and polysaccharides as well as reduced number of microvessels and collagen content compared to those areas without microvascular hypoperfusion. These characteristics might underlie the development of adverse ventricular remodeling in MI patients with extensive MVO.PMID:37506775 | DOI:10.1016/j.aanat.2023.152138

Source: Annals of Anatomy - July 28, 2023 Category: Anatomy Authors: Álvaro Blázquez-Bujeda Maria Ortega Elena de Dios Jose Gavara Nerea Perez-Sol é Tamara Molina-Garcia Victor Marcos-Garc és Ana Diaz Francisco J Chorro Cesar Rios-Navarro Vicente Bod í Amparo Ruiz-Sauri Source Type: research