O-059 Complex clinically-relevant silicone models can be endothelialized and used to visualize and assess vessel injury following catheter simulated use

ConclusionThis work demonstrates that complex, clinically-relevant silicone models can be successfully endothelialized and used to visualize and assess injury following catheter simulated-use. Results were consistent with expected trends based on number of passes and treatment approach, which supports future use of the model to evaluate and compare a variety of neurovascular devices. Overall, this provides a cost-effective, early-stage in vitro model that can precede or complement standard animal testing.Disclosures A. McCulloch: 1; C; This work was funded by Stryker Neurovascular. B. Yang: 1; C; This work was funded by Stryker Neurovascular. S. Frenklakh: 5; C; Employee of Stryker Neurovascular. P. Sah: 5; C; Employee of Stryker Neurovascular. K. Cardinal: 1; C; This work was funded by Stryker Neurovascular.

Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: McCulloch, A., Yang, B., Frenklakh, S., Sah, P., Cardinal, K. Tags: SNIS 20th annual meeting oral abstracts Source Type: research