Incidence of hypocortisolism with long ‐term budesonide irrigation for chronic rhinosinusitis

ConclusionProlonged use of BI alone is not likely to cause hypocortisolemia in the majority of patients. However, concomitant use of inhaled and oral steroids and male sex may be associated with hypocortisolemia. Surveillance of cortisol levels may be considered in vulnerable populations who use BI regularly, particularly in patients using other forms of corticosteroids with known systemic absorption.

Source: International Forum of Allergy and Rhinology - July 24, 2023 Category: Allergy & Immunology Authors: Bruna R. C. Silva, Matthew A. Tyler, Yifei Ma, Jane Wang, Jayakar V. Nayak, Zara M. Patel, Peter H. Hwang Tags: ORIGINAL ARTICLE Source Type: research