Detailed characterization of PD-1/PD-L1 and CTLA4 expression and tumor-infiltrating lymphocytes in yolk sac tumors

CONCLUSION: Generally a high frequency of CTLA4 expression was found, PD-1/PD-L1 expression, the immune-inflamed phenotype, and TLSs were low frequency in YSTs, however, YSTs in testes showed a higher density of TILs and higher expression of immune checkpoint molecules.PMID:37453913 | DOI:10.1016/j.humimm.2023.07.003

Source: Human Immunology - July 15, 2023 Category: Allergy & Immunology Authors: Danya Zhang Hanjie Xu Can Zhao Lingzhi Qin Rui Wei Ling Xi Fei Li Source Type: research