Focus disconnection of the SEEG-identified epileptic network by radiofrequency thermal coagulation

Coagulating much of the epileptogenic lesion (EL) is a favorable prognostic factor for radiofrequency thermocoagulation (RFTC) for focal epilepsy [1]. However, trajectory limitations exist due to the risk of brain tissue and vascular injury around coagulated lesions. It is sometimes challenging to coagulate the entire focus when the EL is large and/or extends over the eloquent area. We propose an RFTC focal disconnection technique that minimizes the number of lesions and trajectories through stereoelectroencephalography (SEEG) monitoring and cortical stimulation mapping (CSM) to estimate the abnormal network consisting of epileptogenic zones and propagation patterns, and intensively coagulating its anomaly network.

Source: Seizure: European Journal of Epilepsy - July 13, 2023 Category: Neurology Authors: Tomotaka Ishizaki, Satoshi Maesawa, Hiroyuki Yamamoto, Miki Hashida, Manabu Mutoh, Yoshiki Ito, Takafumi Tanei, Jun Natsume, Ryuta Saito Source Type: research