Evolving Role of Endoscopic Submucosal Dissection in the Management of Barrett ’s Neoplasia

AbstractPurpose of ReviewWe aim to examine evidence on endoscopic submucosal dissection (ESD) for managing Barrett ’s esophagus related neoplasia by a narrative review.Recent FindingsAvailable studies and meta-analysis indicate ESD has comparable efficacy rates and adverse events as to endoscopic mucosal resection for managing Barrett ’s neoplasia. There is a high rate of en bloc, curative resections for T1a cancers, and early promising data for T1b cancers. However, most data is from expert centers and does not report long-term results. Lesion selection needs to be better defined in future large-scale studies.SummaryThe role of ESD has been expanding in the management of Barrett ’s esophagus-related neoplasia. We need robust data of prospective nature with a precisely defined cohort of patients to determine the efficacy of ESD over EMR and to position this well in the BE armamentarium.
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research