Peer review before trial conduct could increase research value and reduce  waste

Clinical trials have been at the forefront of debates and initiatives toward improving rigor and transparency (e.g., data sharing and registration). However, many problems still plague clinical trials. Selective reporting biases, sloppy methods, p-hacking, and other pitfalls remain prevalent despite efforts from funders, researchers, journals, and patient organizations [1]. According to Chalmers and Glasziou, approximately 85% of medical research goes to waste because of asking the wrong questions or poor design [2].

Source: Journal of Clinical Epidemiology - June 5, 2023 Category: Epidemiology Authors: Maximilian Siebert, Florian Naudet, John P.A. Ioannidis Tags: Commentary Source Type: research