Protocadherin 20 maintains intestinal barrier function to protect against Crohn ’s disease by targeting ATF6

Intestinal barrier dysfunction plays a central role in the pathological onset of Crohn ’s disease. We identify the cadherin superfamily member protocadherin 20 (PCDH20) as a crucial factor in Crohn’s disease. H...

Source: Genome Biology - July 5, 2023 Category: Genetics & Stem Cells Authors: Shanshan Huang, Zhuo Xie, Jing Han, Huiling Wang, Guang Yang, Manying Li, Gaoshi Zhou, Ying Wang, Lixuan Li, Li Li, Zhirong Zeng, Jun Yu, Minhu Chen and Shenghong Zhang Tags: Research Source Type: research