Unraveling Complexities in the Absorption and Disposition Kinetics of Abiraterone via Iterative PBPK Model Development and Refinement

CONCLUSION: Our systematic development of the abiraterone PBPK model has demonstrated its application for the prospective interrogation of the individual or combined influences of potential interindividual variabilities influencing the systemic exposure of abiraterone.PMID:37405634 | DOI:10.1007/s40262-023-01266-y

Source: Clinical Prostate Cancer - July 5, 2023 Category: Cancer & Oncology Authors: Eleanor Jing Yi Cheong Sheng Yuan Chin Zheng Wei Ng Ting Jian Yap Ervin Zhi Bin Cheong Ziteng Wang Eric Chun Yong Chan Source Type: research