GSE227347 Gene expression data from biological replicates of imatinib and nilotinib resistant K-562 cells.

Contributor : Meike KaehlerSeries Type : Expression profiling by arrayOrganism : Homo sapiensResistant cells were generated by stepwise exposure to increasing concentrations of imatinib or nilotinib to establish 0.5 and 2 µM imatinib and 0.05 µM nilotinib resistant cells. This procedure was performed twice independently to establish biological replicates of TKI resistance.We performed microarrays (Clariom S) to analyze the changes in gene expression during the development of TKI resistance.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research