Task ‐dependent functional connectivity of pain is associated with the magnitude of placebo analgesia in pain‐free individuals

ConclusionsResults suggest that stronger expectancy-based placebo responses might be underpinned by greater FC among attentional and somatosensory regions.SignificanceThis article provides support and insight for task-dependent functional connectivity differences related to the magnitude of placebo analgesia. Our findings provide key support that the magnitude of expectation-based placebo response depends on the coupling of regions associated with somatosensory and attentional processing.

Source: European Journal of Pain - June 22, 2023 Category: Anesthesiology Authors: Nicholas J. Bush, Jeff Boissoneault, Janelle Letzen, Roland Staud, Michael E. Robinson Tags: ORIGINAL ARTICLE Source Type: research