Clinical and psychological implications of secondary and incidental findings in cancer susceptibility genes after exome sequencing in patients with rare disorders

Conclusion
SF/IF in CSG were identified in 2.1% of patients. Despite a numerically higher psychological impact, the identification of SF/IF allowed early detection and cancer prevention in families without cancer history.

Source: Journal of Medical Genetics - June 21, 2023 Category: Genetics & Stem Cells Authors: Carrasco, E., Lopez-Fernandez, A., Codina-Sola, M., Valenzuela, I., Cueto-Gonzalez, A., Villacampa, G., Navarro, V., Torres-Esquius, S., Palau, D., Cruellas, M., Torres, M., Perez-Duenas, B., Abuli, A., Diez, O., Sabado-Alvarez, C., Garcia-Arumi, E., Tizz Tags: Cancer genetics Source Type: research