Tertiary Lymphoid Structures are Related to Inflammatory Progression and Bone Loss in Human Apical Periodontitis

Bone loss is strongly associated with the immunological milieu in apical periodontitis (AP). Tertiary lymphoid structures (TLSs) are organized lymphoid cell aggregates that form in nonlymphoid tissues under persistent inflammatory circumstances. To date, there has been no relevant report of TLSs in periapical lesions. This work aimed to investigate the formation and potential function of TLSs in AP.
Source: Journal of Endodontics - Category: Dentistry Authors: Tags: Basic Research-Biology Source Type: research