Cytokine profiling, pretreatment with anakinra, and tolerance development in platinum-induced mixed hypersensitivity reactions

CONCLUSION: In patients with platinum-induced CRR, anakinra could be a useful premedication to block its clinical manifestations, and monitoring of IL-2, IL-5, IL-6, IL-10 and TNF-a could help predict tolerance development thereby allowing safe adjustments to the desensitization protocol and premedication.PMID:37321446 | DOI:10.1016/j.anai.2023.06.011
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research