Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration

Nature Reviews Neurology, Published online: 12 June 2023; doi:10.1038/s41582-023-00822-1Astrocytes are essential for neuronal survival and function in the CNS but, under pathological conditions, they can adopt potentially harmful reactive states. This Review highlights how ‘omics’ technologies can enable the functional characterization of defined reactive astrocyte states in various pathological scenarios.

Source: Nature Reviews Neurology - June 12, 2023 Category: Neurology Authors: Rickie Patani Giles E. Hardingham Shane A. Liddelow Source Type: research