Rapid Reduction in Staphylococcus aureus in Atopic Dermatitis Subjects Following Dupilumab Treatment

Dupilumab reduces lesional S. aureus abundance and virulence factor production within three days. These changes likely occur through enhancement of innate immune responses linked to IL-17, as well as neutrophil and complement activation.

Source: Journal of Allergy and Clinical Immunology - June 12, 2023 Category: Allergy & Immunology Authors: Eric L. Simpson, Patrick M. Schlievert, Takeshi Yoshida, Stephanie Lussier, Mark Boguniewicz, Tissa Hata, Zelma Fuxench, Anna De Benedetto, Peck Y. Ong, Justin Ko, Agustin Calatroni, Amanda K. Rudman Spergel, Marshall Plaut, Sally A. Quataert, Samuel H. K Source Type: research