Sufentanil inhibits Pin1 to attenuate renal tubular epithelial cell ischemia –reperfusion injury by activating the PI3K/AKT/FOXO1 pathway

ConclusionSufentanil reduced Pin1 expression through activation of the PI3K/AKT/FOXO1 signaling to suppress cell apoptosis, oxidative stress and inflammation in renal tubular epithelial cells during RIRI development.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research