Targeting ALK1 to block LDL transcytosis and halt atherosclerosis

Nature Reviews Cardiology, Published online: 02 June 2023; doi:10.1038/s41569-023-00895-xIn a mouse model of atherosclerosis, a selective monoclonal antibody that blocks the binding of LDL to activin receptor-like kinase 1 reduced plaque formation in the aorta.

Source: Nature Reviews Cardiology - June 2, 2023 Category: Cardiology Authors: Karina Huynh Source Type: research