A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes
Gao and colleagues identify eight loci of breast cancer susceptibility in a genome-wide association study. By leveraging gene expression data from multiple tissues, they also discover 309 breast cancer susceptibility genes in a transcriptome-wide association study. Known genetic risk variants could act on these genes to cause breast cancer.
Source: The American Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Guimin Gao, Peter N. Fiorica, Julian McClellan, Alvaro N. Barbeira, James L. Li, Olufunmilayo I. Olopade, Hae Kyung Im, Dezheng Huo Tags: Article Source Type: research