A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes

Gao and colleagues identify eight loci of breast cancer susceptibility in a genome-wide association study. By leveraging gene expression data from multiple tissues, they also discover 309 breast cancer susceptibility genes in a transcriptome-wide association study. Known genetic risk variants could act on these genes to cause breast cancer.
Source: The American Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research