Impact of pregnancy on polyfunctional IgG and memory B cell responses to Tdap immunization

CONCLUSIONS: This study demonstrates that pregnancy does not affect the quality of effector IgG and memory B cell responses to Tdap immunization and that polyfunctional IgG are efficiently transferred across the placenta.REGISTRY'S URL AND THE TRIAL'S REGISTRATION NUMBER: ClinicalTrials.Gov (NCT03519373).PMID:37244810 | DOI:10.1016/j.vaccine.2023.05.035

Source: Vaccine - May 27, 2023 Category: Allergy & Immunology Authors: Martin Taton Fabienne Willems Cyprien Widomski Charlotte Martin Yiwei Jiang Katty Renard Alexandra Cogan Coca Necsoi Margaret E Ackerman Arnaud Marchant Nicolas Dauby Source Type: research