Wavelength-dependent error minimization for quantitative spectroscopic photoacoustic tomography with a ring-array system

CONCLUSIONS: Utilizing UST for model-based optical and acoustic compensation of PAT images was proposed by our group previously. In this work, we further demonstrated the efficacy of the developed algorithm in sPAT by minimizing the error caused by the tissue's optical heterogeneity on improving spectral unmixing, which is a major limiting factor in reliability of sPAT measurements. Such synergistic combination of UST and PAT provides a window of opportunity to achieve bias-free quantitative sPAT measurements, which plays an important role in future pre-clinical and clinical utility of PAT.PMID:37225605 | DOI:10.1016/j.zemedi.2023.04.005
Source: Zeitschrift fur Medizinische Physik - Category: Radiology Authors: Source Type: research