Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank

Acute knee injury is associated with post-traumatic OA (PTOA). Very little is known about the genome-wide associations of PTOA when compared with idiopathic OA (iOA). Our objective was to describe the development of knee OA after knee injury and its genetic associations in UK Biobank (UKB).

Source: Osteoarthritis and Cartilage - May 27, 2023 Category: Rheumatology Authors: B Hollis, C Chatzigeorgiou, L Southam, K Hatzikotoulas, S Kluzek, A Williams, E Zeggini, L Jostins-Dean, FE Watt, the Genetics of Osteoarthritis Consortium Source Type: research