ScRNA-seq revealed an immunosuppression state and tumor microenvironment heterogeneity related to lymph node metastasis in prostate cancer

ConclusionsThe significant heterogeneity of luminal, immune, and interstitial cells in PCa LNM may not only directly contribute to tumor progression, but also indirectly result  in TME immunosuppression, which may be the cause of metastasis in PCa and in which MYC played an role.
Source: Experimental Hematology and Oncology - Category: Cancer & Oncology Source Type: research