Do matrix metalloproteinase and cathepsin K inhibitors work synergistically to reduce dentin erosion?

CONCLUSIONS: The inhibition of endogenous dentinal MMPs and catK increases the acid resistance of human dentin but without an apparent synergistic effect. The inhibition of MMPs and catK is equally effective either before or after the acid challenge.PMID:37162106 | PMC:PMC10167948 | DOI:10.1590/1678-7757-2022-0449

Source: Appl Human Sci - May 10, 2023 Category: Physiology Authors: Xiujiao Lin Xinwen Tong Hui Yang Yiying Chen Hao Yu Source Type: research