The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections

A Trial within Cohorts (TwiCs) study design is a trial design that uses the infrastructure of an observational cohort study to initiate a randomized trial. Upon cohort enrollment, the participants provide cons...

Source: BMC Medical Research Methodology - May 13, 2023 Category: Research Authors: Rob Kessels, Anne M. May, Miriam Koopman and Kit C. B. Roes Tags: Research Source Type: research