Breast Cancers with a HER2/CEP17 Ratio of 2.0 or Greater and an Average HER2 Copy Number of Less Than 4.0 per Cell: Frequency, Characteristics and Survival Outcomes in those Receiving HER2-targeted Treatment

Purpose: 2018 ASCO CAP testing guidelines for HER2 recommended a change from ‘positive’ to ‘negative’ in cases of IHC 2+, FISH HER2/CEP17 ratio ≥2.0 and HER2 copy number

Source: Clinical Oncology - May 6, 2023 Category: Radiology Authors: G. Patel, Y.-C. Lam, J. Brown, G. Donald, C. Harper-Wynne Source Type: research