Multicenter Population Pharmacokinetics and Exposure –Efficacy Analysis of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

ConclusionsIn patients with IPF, covariates such as bodyweight and food might not be sufficient for dose adjustment, and a low dose of 1500 mg/day could also provide 80% of theEmax, as the standard dose (1800 mg/day).
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research