Platelet-Rich Plasma Versus Corticosteroid Injection in the Treatment of Arthropathic Chronic Low Back Pain: Systematic Review and Meta-analysis

AbstractPurpose of ReviewLow back pain (LBP) is the leading cause of global disability. Recently, there has been an interest in using platelet-rich plasma (PRP) to relieve pain and improve functional status in patients with chronic LBP. We performed a systematic review with meta-analysis to compare the clinical efficacy of PRP against corticosteroid for the treatment of LBP.Recent FindingsRecent randomized controlled trials have suggested that PRP injections may have additional benefit over corticosteroid injections for the treatment of LBP.SummaryIn our pooled analysis, the corticosteroid group was found to have reduced pain and Oswestry Disability Index (ODI) scores compared to PRP at 1 month but there was no significant difference at 3 and 6 months. There is some evidence to suggest that PRP may be more effective for long-term pain reduction.
Source: Current Physical Medicine and Rehabilitation Reports - Category: Rehabilitation Source Type: research