Periostin acts as a bridge between gestational diabetes mellitus (GDM) and chronic inflammation to modulate insulin resistance by modulating PPAR α/NF-κB/TNF-α signaling pathway

CONCLUSION: POSTN levels were significantly higher in pregnant women with GDM and were associated with chronic inflammation and PPARα expression. POSTN may act as a bridge between GDM and chronic inflammation to modulate insulin resistance by modulating PPARα/NF-κB/TNF-α signaling pathway.PMID:37106515 | DOI:10.2174/1871530323666230427104724

Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 28, 2023 Category: Endocrinology Authors: Qun Ji Xinying Li Yan Wang Haiwei Liu Kaining Chen Huibiao Quan Huachuan Zhang Jianmin Ran Source Type: research