Prediction of Radiation-induced Lymphopenia following Exposure of the Thoracic Region and Associated Risk of Infections and Mortality

Large blood volumes are irradiated when the heart is exposed to radiation. The mean heart dose (MHD) may be a good surrogate for circulating lymphocytes exposure. We investigated the association between MHD and radiation-induced lymphopenia and explored the impact of the end-of-radiation-therapy (EoRT) lymphocyte count on clinical outcomes.

Source: Clinical Oncology - April 18, 2023 Category: Radiology Authors: C. Terrones-Campos, B. Ledergerber, N. Forbes, A.G. Smith, J. Petersen, M. Helleberg, J. Lundgren, L. Specht, I.R. Vogelius Tags: Original Article Source Type: research