NF- κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss

Inflammaging represents an accepted concept where the immune system shifts to a low-grade chronic pro-inflammatory state without overt infection upon aging. In the CNS, inflammaging is mainly driven by glia ce...

Source: Molecular Neurodegeneration - April 17, 2023 Category: Neurology Authors: Judith Stefanie Schlett, Melanie Mettang, Aladdin Skaf, Pavel Schweizer, Alina Errerd, Ephraim Alemayehu Mulugeta, Tabea Melissa Hein, Konstantinos Tsesmelis, Miltiadis Tsesmelis, Ulrike F. G. B üttner, Heinrich Wendt, Alireza Abaei, Volker Rasche, Vivie Tags: Research article Source Type: research